Abstract Background Ramucirumab (RAM), a monoclonal antibody for vascular endothelial growth factor 2 (VEGFR2), has been effective for advanced gastric adenocarcinoma (AC). However, little is known about the efficacy of…
Identification of the site of origin for ‘malignancy with unknown primary’ remains a challenge for modern pathology. Correct diagnosis is critical to defining the most beneficial treatment for the patient.…
Abstract Objective: To assess clinicopathological characteristics of primary gastro-entero-pancreatic poorlydifferentiated neuroendocrine carcinomas (GEP-PDNECAs) and evaluate overall survival in patients treatedwith systemic platinum and etoposide therapy.Methods: A detailed retrospective review of…
Abstract Objectives— Using gene expression profiling on frozen primary pancreatic endocrine tumors (PETs), we discovered RUNX1T1 as a leading candidate progression gene. This study was designed (1) to validate the…
Editors: Aejaz Nasir, Domenico CoppolaPublisher: Springer-Verlag, New YorkLanguage: EnglishYear: 2016eBook ISBN: 978-1-4939-3426-3Hardcover ISBN: 978-1-4939-3424-9No. of pages: XIII, 543 The first edition of “Neuroendocrine Tumors: Review of Pathology, Molecular and Therapeutic…
Abstract A robust immunohistochemical (IHC) assay for VEGFR2 was developed to investigate its utility for patient tailoring in clinical trials. The sensitivity, specificity, and selectivity of the IHC assay were…
Abstract. Background: Palladin is a metastasis-associated gene regulating cell motility. The expression of palladin protein in pancreatic neuroendocrine tumors (PET) and carcinomas (PECA) is not known. Materials and Methods: A…
Abstract Background: Understanding the concept of resuscitation is extremely important in the professional life of all healthcare workers. By achieving the appropriate resuscitation knowledge and psychomotor skills, the efficacy of…
GOALS AND OBJECTIVES:1- To develop and implement a well-interrogated global strategy to support national and international recognition of our alma mater.2- To bring most accomplished IQBALIANS together to build a…