Abstract Background: the vascular endothelial growth factor (VEGF) pathway plays a prominent role in the growth and progression of human cancer, including non-small cell lung carcinoma (NSCLC). The key mediators...
READ MORE-
President's Message
What a journey it has been. Let me personally thank each and every one of you who has contributed in these foundational stages of AIMC-GTT in terms of time, money and effort. -
Promoting Healthy Lives
We aim to change the conversation to focus on health as an asset, rather than ill health as a burden – and to promote policies and encourage local action that improves opportunities for a healthy life in the PAKISTAN. -
Improving National Health Care & Policy
Our policy team’s work focuses on supporting more evidence-informed policies on health and social care, contributing to better health for people in the PAKISTAN.
Featured Content
DISCOVER
![](https://aimcthinktank.com/wp-content/uploads/2023/07/healthy_lives_evidence_hub_column.png)
Evidence hub: What drives health inequalities?
Data, insights and analysis exploring how the circumstances in which we live shape our health
PODCAST
![](https://aimcthinktank.com/wp-content/uploads/2023/07/Podcast-episode-33_NHS-at-75-political-leadership_Thumbnail.png)
NHS at 75: Is political leadership up to the challenge? – with Alan Milburn and Stephen Dorrell
Episode 33|29 June 2023|31 mins Episode 33 of the Health Foundation podcast
Our Latest Publications & Long Reads
CHARTS
![](https://aimcthinktank.com/wp-content/uploads/2023/07/NHS-at-75-social-share.png)
How the public views the NHS at75
Six findings on how the public views the NHS at 75 and perceptions of what the future may bring.
LONG READ
![](https://aimcthinktank.com/wp-content/uploads/2023/07/NHS-improvement-thumbnail-2.png)
Five principles for implementing the NHS Impact approach to improvement in PAKISTAN
21 April 2023 | 18 mins to read To support the implementation of the new NHS Impact approach to improvement, this long read sets out...
Articles that medical Professionals will actually want to read
![](https://aimcthinktank.com/wp-content/uploads/2023/07/medical04.jpg)
About Sweet Home
We Take Care of Your Problems Carefully
Greatest properly off ham exercise all. Unsatiable invitation its possession nor off. All difficulty estimating unreserved increasing the solicitude. Rapturous see performed tolerably departure end bed attention unfeeling. On unpleasing principles alteration of.
- Maids table how learn drift but purse stand.
- Music me house could among oh as their.
- Rendered her for put improved concerns his.
Who We Are
What We Provide
Greatest properly off ham exercise all. Unsatiable invitation its possession nor off. All difficulty estimating unreserved increasing the solicitude. Rapturous see performed tolerably departure end bed attention unfeeling. On unpleasing principles.
Personalized Care Assistance
Allow miles wound place the leave had. To sitting subject no improve studied limited. Ye indulgence unreserved connection alteration appearance my an astonished.
Medication Management
Allow miles wound place the leave had. To sitting subject no improve studied limited. Ye indulgence unreserved connection alteration appearance my an astonished.
Assisted Bathing and Dressing
Allow miles wound place the leave had. To sitting subject no improve studied limited. Ye indulgence unreserved connection alteration appearance my an astonished.
![](https://aimcthinktank.com/wp-content/uploads/2023/07/pic-16.jpg)
![](https://aimcthinktank.com/wp-content/uploads/2023/07/pic-12.png)
![](https://aimcthinktank.com/wp-content/uploads/2023/07/pic-14.png)
![](https://aimcthinktank.com/wp-content/uploads/2023/07/pic-13.png)
![](https://aimcthinktank.com/wp-content/uploads/2023/07/pic-15.png)
Partnerships for authentic experiences.
Nemo enim ipsam voluptatem quia voluptas.
“Sed quia consequuntur magni dolores eos qui ratione voluptatem sequi nesciunt. Neque porro quisquam est, qui dolorem ipsum quia dolor sit amet, consectetur, adipisci velit. sed quia non numquam qui ratione voluptatem sequi nesciunt.
![](https://aimcthinktank.com/wp-content/uploads/2023/07/t7.jpg)
![](https://aimcthinktank.com/wp-content/uploads/2023/07/medical02.jpg)
Why Choose Us
We Are Home Care With Best Experience
Greatest properly off ham exercise all. Unsatiable invitation its possession nor off. All difficulty estimating unreserved increasing the solicitude. Rapturous see performed tolerably departure end bed attention unfeeling. On unpleasing principles alteration of.
We provide supportive, compassionate and highly qualified nurses for all your nursing and medical needs
Emergency Call
+1-(318) 766-9161
![](https://aimcthinktank.com/wp-content/uploads/2023/07/Annabella-Mathews.png)
Annabella Mathews
Founder
Greatest properly off ham exercise all. Unsatiable invitation its possession nor off. All difficulty estimating unreserved increasing the solicitude. Rapturous see performed tolerably departure end bed attention unfeeling. On unpleasing principles alteration of.
- Style too own civil out along.
- Need eat week even yet that.
- Silent sir say desire fat him letter.
- Effect if in up no depend seemed.
- Style too own civil out along.
- Need eat week even yet that.
- Silent sir say desire fat him letter.
- Effect if in up no depend seemed.
![](https://aimcthinktank.com/wp-content/uploads/2023/07/pic-18.jpg)
Feedback
Stories From Our Patients
![John Doe](https://aimcthinktank.com/wp-content/uploads/2023/07/testimonial-1.jpg)
"Lorem ipsum dolor sit amet, consectetur adipiscing elit. Curabitur laoreet cursus volutpat. Aliquam sit amet ligula et justo tincidunt laoreet non vitae lorem. Aliquam porttitor tellus enim, eget commodo augue porta ut. Maecenas lobortis ligula vel tellus sagittis ullamcorperv."
![Tom Jones](https://aimcthinktank.com/wp-content/uploads/2023/07/testimonial-2.jpg)
"Lorem ipsum dolor sit amet, consectetur adipiscing elit. Curabitur laoreet cursus volutpat. Aliquam sit amet ligula et justo tincidunt laoreet non vitae lorem. Aliquam porttitor tellus enim, eget commodo augue porta ut. Maecenas lobortis ligula vel tellus sagittis ullamcorperv."
![Mark Wilson](https://aimcthinktank.com/wp-content/uploads/2023/07/testimonial-3.jpg)
"Lorem ipsum dolor sit amet, consectetur adipiscing elit. Curabitur laoreet cursus volutpat. Aliquam sit amet ligula et justo tincidunt laoreet non vitae lorem. Aliquam porttitor tellus enim, eget commodo augue porta ut. Maecenas lobortis ligula vel tellus sagittis ullamcorperv."
24/7 Availability
We Are Available For Home Care Consultation
Greatest properly off ham exercise all. Unsatiable invitation its possession nor off. All difficulty estimating unreserved increasing the solicitude. Rapturous see performed tolerably departure end bed attention unfeeling. On unpleasing principles alteration of.
Latest News
Get To Know More From
Our Blogs & News
- All Post
- Journal Articles
- News and Comments
- Symposia
Abstract Historical data have indicated the potential for the histologically-normal breast to harbor pre-malignant changes at the molecular level.…
Abstract We recently developed a malignancy-risk gene signature that was shown to identify histologically-normal tissues with a cancer-like profile.…
Abstract Background: A postgraduate training program should be focused on positive and healthy educational environment. Postgraduate trainees suffer invariably…
Turn to bright solutions and elevate your decor with ceiling lights
Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis
Call To Action
Main Heading
Aliquet adipiscing vivamus ultrices ipsum, commodo vitae, elit nec ipsam luctus. Eget non vitae scelerisque eget sapiente libero, lorem nam quis vitae quis morbi, id consequat mauris massa. Nibh sed accumsan pede gravida nec.
Proliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue
Abstract Historical data have indicated the potential for the histologically-normal breast to harbor pre-malignant changes at the molecular level. We postulated that a histologically-normal tissue with ‘‘tumor-like’’ gene expression pattern...
READ MOREEvaluation of malignancy-risk gene signature in breast cancer patients
Abstract We recently developed a malignancy-risk gene signature that was shown to identify histologically-normal tissues with a cancer-like profile. Because the signature was rich with proliferative genes, we postulated it...
READ MOREMeasuring Cross-Cultural Perception of Educational Environment among Postgraduates by Using Postgraduate Hospital Educational Environment Measure (PHEEM) Inventory
Abstract Background: A postgraduate training program should be focused on positive and healthy educational environment. Postgraduate trainees suffer invariably during their training when the hospital educational environment is stressful. It...
READ MOREStromal-Based Signatures for the Classification of Gastric Cancer
Abstract Treatment of metastatic gastric cancer typically involves chemotherapy and monoclonal antibodies targeting HER2 (ERBB2) and VEGFR2 (KDR). However, reliable methods to identify patients who would benefit most from a...
READ MOREHeterogeneity of Vascular Endothelial Growth Factor Receptors1, 2, 3 in Primary Human Colorectal Carcinoma
Abstract. Background: The vascular endothelial growth factor (VEGF) pathway plays an important role in growth and progression of human cancer, including colorectal carcinomas (CRC). The key mediators of VEGF signaling...
READ MORESomatostatin Receptor Profiling in Hepatic Metastases From Small Intestinal and Pancreatic Neuroendocrine Neoplasms: Immunohistochemical Approach With Potential Clinical Utility
Background: The expression of somatostatin receptors (SSTRs) on endocrine tumor (ET) cells forms the basis for somatostatin analog treatment of patients with SSTR-positive, hormonally active ETs. In patients with SSTRnegative...
READ MOREDifferential expression of VEGFR2protein in HER2 positive primary human breastcancer: potential relevance to anti‑angiogenictherapies
Abstract Background: Clinically relevant predictive biomarkers to tailor anti-angiogenic therapies to breast cancer (BRC) patient subpopulations are an unmet need.Methods: We analyzed tumor vascular density and VEGFR2 protein expression in...
READ MOREEfficacy and safety of ramucirumabcontaining chemotherapy in patients with pretreated metastatic gastric neuroendocrine carcinoma
Abstract Background Ramucirumab (RAM), a monoclonal antibody for vascular endothelial growth factor 2 (VEGFR2), has been effective for advanced gastric adenocarcinoma (AC). However, little is known about the efficacy of...
READ MOREHybrid Model Integrating Immunohistochemistry andExpression Profiling for the Classification ofCarcinomas of Unknown Primary Site
Identification of the site of origin for ‘malignancy with unknown primary’ remains a challenge for modern pathology. Correct diagnosis is critical to defining the most beneficial treatment for the patient....
READ MORESoft & full grid post style
Display your blog post individually in full grid view on a light background
Profiling of Vascular Endothelial Growth Factor Receptor Heterogeneity Identifies Protein Expression-defined Subclasses of Human Non-small Cell Lung Carcinoma
Abstract Background: the vascular endothelial growth factor (VEGF) pathway plays a prominent role in the growth and progression of human cancer, including non-small cell lung carcinoma (NSCLC). The key mediators of VEGF signaling are a family of related receptor tyrosine kinases that include VEGFR1, VEGFR2, and VEGFR3. The relative expression…
Proliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue
Abstract Historical data have indicated the potential for the histologically-normal breast to harbor pre-malignant changes at the molecular level. We postulated that a histologically-normal tissue with ‘‘tumor-like’’ gene expression pattern might harbor substantial risk for future cancer development. Genes associated with these high-risk tissues were considered to be ‘‘malignancy-risk genes’’.…
Abstract We recently developed a malignancy-risk gene signature that was shown to identify histologically-normal tissues with a cancer-like profile. Because the signature was rich with proliferative genes, we postulated it might also be prognostic for existing breast cancers. We evaluated the malignancy risk gene signature to see its clinical association…
Measuring Cross-Cultural Perception of Educational Environment among Postgraduates by Using Postgraduate Hospital Educational Environment Measure (PHEEM) Inventory
Abstract Background: A postgraduate training program should be focused on positive and healthy educational environment. Postgraduate trainees suffer invariably during their training when the hospital educational environment is stressful. It is, therefore very important to assess the training environment of an institute as a part of good educational practice.Aims: The…
Abstract Treatment of metastatic gastric cancer typically involves chemotherapy and monoclonal antibodies targeting HER2 (ERBB2) and VEGFR2 (KDR). However, reliable methods to identify patients who would benefit most from a combination of treatment modalities targeting the tumor stroma, including newimmunotherapy approaches, are still lacking. Therefore, we integrated a mouse model…
Heterogeneity of Vascular Endothelial Growth Factor Receptors1, 2, 3 in Primary Human Colorectal Carcinoma
Abstract. Background: The vascular endothelial growth factor (VEGF) pathway plays an important role in growth and progression of human cancer, including colorectal carcinomas (CRC). The key mediators of VEGF signaling are VEGFR1, VEGFR2, and VEGFR3, part of a family of related receptor tyrosine kinases. The relative expression, activity, or interplay…
Somatostatin Receptor Profiling in Hepatic Metastases From Small Intestinal and Pancreatic Neuroendocrine Neoplasms: Immunohistochemical Approach With Potential Clinical Utility
Background: The expression of somatostatin receptors (SSTRs) on endocrine tumor (ET) cells forms the basis for somatostatin analog treatment of patients with SSTR-positive, hormonally active ETs. In patients with SSTRnegative ETs, the clinical response is generally absent or suboptimal, while nonfunctioning ETs with SSTR positivity show a variable response to…
Differential expression of VEGFR2protein in HER2 positive primary human breastcancer: potential relevance to anti‑angiogenictherapies
Abstract Background: Clinically relevant predictive biomarkers to tailor anti-angiogenic therapies to breast cancer (BRC) patient subpopulations are an unmet need.Methods: We analyzed tumor vascular density and VEGFR2 protein expression in various subsets of primary human BRCs (186 females; Mean age: 59 years; range 33–88 years), using a tissue microarray. Discrete…
Efficacy and safety of ramucirumabcontaining chemotherapy in patients with pretreated metastatic gastric neuroendocrine carcinoma
Abstract Background Ramucirumab (RAM), a monoclonal antibody for vascular endothelial growth factor 2 (VEGFR2), has been effective for advanced gastric adenocarcinoma (AC). However, little is known about the efficacy of RAM-containing chemotherapy (RAM-CTx) in gastric neuroendocrine carcinoma (G-NEC).Methods We retrospectively analysed and compared the clinical outcomes of patients (pts) with…
Hybrid Model Integrating Immunohistochemistry andExpression Profiling for the Classification ofCarcinomas of Unknown Primary Site
Identification of the site of origin for ‘malignancy with unknown primary’ remains a challenge for modern pathology. Correct diagnosis is critical to defining the most beneficial treatment for the patient. Standard pathological approaches combine morphology and immunohistochemical (IHC) studies to first subclassify cytokeratin-positive carcinomas into adenocarcinoma, squamous cell carcinoma, neuroendocrine…